Chiropractic, Oxidative Stress & DNA Repair
From Dr. Matthew McCoy - Editor - Journal of Vertebral Subluxation Research
The more I read of the literature on aging the more I become aware of how far off track our profession has gone when it comes to research. While other professions are digging deeply into the role of the nervous and immune systems on aging, apoptosis, DNA repair, genetic expression etc., the research leadership in our profession continues to focus on back pain.
What role does the subluxation and adjustment play in these areas? Fortunately, one group of researchers is looking into it and we recently published their work in JVSR.
This article explains what we mean when we teach our patients that chiropractic is not just about back pain.
Surrogate Indication of DNA Repair in Serum After Long Term Chiropractic Intervention - A Retrospective Study [February 18, 2005, pp 1-5]
Objective: To assess the effects of short-term and long-term chiropractic care on serum thiol levels in asymptomatic subjects.
Summary of background data: Serum thiols are a measure of human health status. It is a surrogate estimate of DNA repair enzyme activity, most notably poly ADP - ribose polymerase or PARP. While it is suggested that chiropractic care improves general health, the effect of chiropractic care on serum thiol levels has not been investigated.
Methods: A case controlled retrospective analysis. Serum thiol levels in patients with active disease (N=46) were compared with serum thiol levels in primary wellness subjects with 8-52 weeks of chiropractic care (N=21) and those who had been under chiropractic care for 52-312 weeks (N=25). Patients were age matched to be 40 years of age or older.
Results: There were statistically significant differences in the serum thiol levels of the three groups. Mean serum thiol levels were lowest in patients with active disease as well as patients with initial musculoskeletal complaints. Asymptomatic subjects under chiropractic care demonstrated higher mean serum thiol levels than patients with active disease. Mean serum thiol levels were highest in the group with 52-312 weeks of chiropractic care.
Conclusion: Asymptomatic or primary wellness subjects under chiropractic care demonstrated higher mean serum thiol levels than patients with active disease and produced some values that were higher than normal wellness values.
"Dedicated to providing my patients with the holistic therapies and personalized education they need to regain and maintain their optimal health."
Therapies Offered: Spinal & Extremity Manipulation, Applied Kinesiology, Sacral-Cranial Work, Meridian Acu-Point Therapy, Organ Lymphatic & Vascular Reflex Work, Muscle Balancing, Nutritional Consultation, Bio-impedance Analysis
www.drvittoriarepetto.meta-ehealth.com
One of the top ten NYC chiropractors, New Life magazine, Sept 2001
Best doctor - best of New York - N Y Blade, Oct 17, 2003 (Http://nyblade.com/2003/10-17/arts/bestofny/)
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